TY - JOUR AU - Deribie, Awoke AU - Mihret, Adane AU - Demisie, Yohannes AU - Abebe, Tamrat PY - 2016/02/09 Y2 - 2024/03/29 TI - Bacteriological profile of burn patients at Yekatit 12 Hospital Burn Center, Ethiopia: A longitudinal study JF - The Ethiopian Journal of Health Development JA - EJHD VL - 28 IS - 1 SE - Original Articles DO - UR - https://ejhd.org/index.php/ejhd/article/view/12 SP - AB - <p class="p1"> </p><p class="p2"><span class="s1"> </span><strong>Introduction</strong>: Burn is one of the most common devastating and a very painful form of trauma. Significant thermal injuries induce a state of immune-suppression that predisposes burn patients to infection complications. </p><p class="p2"><strong>Materials and methods</strong>: A prospective hospital based study was carried out from December 2010 to February 2011 at Yekatit 12 hospital burn center. Periodic wound swabs and blood samples were collected on 1<span class="s2"><sup>st</sup></span>, 7<span class="s2"><sup>th</sup></span>, and 14<span class="s2"><sup>th </sup></span>days of hospital stay and processed with conventional culture and biochemical tests. Isolates were tested against commonly used antibiotics by Modified Kirby-Bauer disc diffusion methods. Data were analyzed by SPSS version 17.0 for Windows. </p><p class="p2"><strong>Results</strong>: From the total of 104 pus cultures, 101 isolates were identified. At the 1<span class="s2"><sup>st </sup></span>day of pus culture the dominant isolate was <em>Staphylococcus aureus </em>15(46.9%). On the 7<span class="s2"><sup>th </sup></span>day of pus culture <em>S. aureus </em>21 (46.1%) and <em>Pseudomonas spp </em>20 (44.4%) were isolated. Similarly, at the 14<span class="s2"><sup>th </sup></span>day the most frequent isolates were <em>S. aureus </em>12 (50%) <em>and Pseudomonas spp</em>11 (45.8 %). There was no significant change on time regarding blood culture isolates. Of 92 blood cultures, 15 gram positive isolates were identified the majority being coagulase negative staphylococci (CoNS), 8 (53.3%). Gram negative isolates, mainly <em>Pseudomonas spp </em>were found resistant for most of antibiotics used in the hospital. </p><p class="p2"><strong>Conclusions: </strong>The nature of periodic microbial wound colonization, flora changes and their antibiotic susceptibility pattern should be taken into consideration in empirical antimicrobial treatment of burned patients. [<em>Ethiop. J. Health Dev. </em>2014;28(1):40-44] </p> ER -