Application Value of Comprehensive Nursing Intervention in Sorafenib Targeted Therapy for Advanced Liver Cancer

Abstract

Abstract Background: The liver is affected by various types of cancer, of which the most common type is hepatocellular carcinoma. Its first symptom is found in the hepatocyte cells of the liver. There are also other types of cancer in the liver, though less common, such as hepatoblastoma and intrahepatic cholangiocarcinoma.Objective: The aim of this paper is to study the application value of comprehensive nursing intervention in sorafenib targeted therapy for advanced liver cancer.Methods: 40 patients with advanced hepatocellular carcinoma were included in this study, and oral sorafenib was taken twice a day. For the patients in the observation group, the usual method was used for their treatment, along with the comprehensive care method. Combined molecular targeted therapy is a relatively new method currently used in the treatment of primary liver cancer in our country's medical community.Results and Discussions: Following the administration of the drug sorafenib, patients developed severe diarrhoea and pancreatic atrophy. When the phenomenon of atrophy occurs, the treatment effect for patients with primary liver cancer is more apparent. Comprehensive care for patients with advanced liver cancer, including comprehensive scientific and reasonable care from the psychological, physical, and mental diet of patients can effectively control and relieve various adverse emotions of patients, thereby improving the patients' triumph over pain and the disease.Conclusion: With confidence and courage, implementing comprehensive care can effectively improve the patient's quality of life. [Ethiop. J. Health Dev.2022: 36(1):00-00]Key words: Comprehensive nursing intervention; Sorafenib; Targeted therapy; Mid-advanced liver cancer