EFFICACY OF T CELL SUBSETS IN EVIDENCE-BASED NURSING AFTER PRIMARY SCLEROSING CHOLANGITIS

T CELL SUBSETS IN EVIDENCE-BASED NURSING AFTER PRIMARY SCLEROSING CHOLANGITIS

Abstract

Background: Primary sclerosing cholangitis (PSC) is a rare, chronic cholestatic liver disease described by bile duct fibrosis and intrahepatic or extrahepatic stricture, or both. Bile duct and liver inflammation and fibrosis are followed by poor bile generation or flow and increasing liver dysfunction. Patients may appear with symptoms such as pruritus, tiredness, right upper quadrant discomfort, recurrent cholangitis, or portal hypertension sequelae. Fatigue, pruritus, malabsorption syndrome, sicca syndrome, osteoporosis, and the obstacles of managing with chronic disease all have an influence on the patient's quality of life. Method: To distinguish this rare disease from PSC, autoimmune hepatitis, obstructed bile duct lesions, drug-induced cholestasis, cholestasis in pregnancy, cholangio carcinoma, hepatic malignancy, and peptic ulcer, advanced practice registered nurses must appreciate the pathophysiology, medical appearance, analytic techniques, illness and indication treatment, and precedence nursing measurement and care in sufferers. Results and Discussions: EBN (Evidence-Based Nursing) is a strategy of creating worth judgments and providing nursing treatment depending upon the individual medical understanding and the current statistics. So, this study is looking at the influence of EBN on the effectiveness of t-cell subsets in PSC patients' demographic characteristics. To begin, data on patients with PSC are acquired using an inclusion/exclusion method. A control team and an investigating team were formed, with each having its own specialized set of responsibilities. The control group receives a normal therapy, whereas the study group receives evidence-based nursing care (EBN). PSC patients' conditions are assessed using the Fisher exact test, ANOVA test and Chi- Square test. As a result of this study, the effectiveness of t-cell subsets in PSC patients' outcomes may be better monitored by nurses. To ensure that our study is as successful as possible, we compare our findings to current nursing models.