Application of Michigan nerve screening scale in the screening of diabetic peripheral neuropathy in China

Michigan nerve screening scale in the screening of diabetic peripheral neuropathy

Abstract

Objective: The purpose of this study was to investigate the diagnostic value of the Michigan nerve screening scale (MNSI) in the detection of diabetic peripheral neuropathy. Methods: 206 patients with Type 2 diabetes were screened with the Michigan nerve screening scale (questionnaire score). The patients were separated into two groups: DPN and non-DPN (EMG) as per the electromyography, The patients were divided into the DPN group and non-DPN group according to the electromyography (EMG). The diagnostic value of Michigan nerve screening scale was evaluated by diagnostic test and ROC curve analysis, and the appropriate cut off point was found. Kappa values were calculated with four tables to determine the correlation between Michigan nerve screening scale and gold standard electromyography. Results: The area under ROC curve (AUC) of MNSI questionnaire was 0.907(p < 0.01), 95% CI (0.861 0.952). When MNSI questionnaire scores 4 act as the cutoff, the sum of sensitivity and specificity was the maximum, and the Kappa was 0.754(p< 0.01). Conclusions: The MNSI questionnaire can be utilized to assess for diabetic peripheral neuropathy early on. The suggested cut-off points should be 4. The questionnaire is consistent with the gold standard electromyography. It is especially suitable for hospitals in remote areas, which are temporarily unable to afford the expensive equipment needed to screen for neuropathy.