Therapeutic effect of exercise rehabilitation combined with huatuo reconstructive pills on vascular dementia

Huatuo reconstructive pills on vascular dementia

Abstract

Background: Vascular dementia is the second most threatening brain disease, following the Alzeimer’s disease, effectuated by the suspension of normal blood flow in the brain as a result of a blockage that is caused by cerebrovascular diseases such as stroke.   Objective: Our aim of carrying out this project is to explore the therapeutic effect and significance of exercise rehabilitation combined with huatuo reconstructive pill in the treatment of vascular dementia and to understand the cause of its effect on social determinants health development. Materials and Methods: 80 patients with vascular dementia were selected for this. Patients were randomly divided into an observation group and control group with 40 cases each. The control group was given huatuo reconstructive pill orally on the basis of conventional treatment, and the observation group was given exercise rehabilitation training on the basis of the control group. The two groups were compared before and after treatment with MMSE score, Barthel index (BI) score, blood lipid, vascular function and neurotransmitter related indicators. Results: After 1 course of treatment, the total effective rate of the observation group was significantly higher than that of the control group (P < 0.05). The directivity, language ability and total MMSE scores of patients in the observation group and the control group were significantly higher after treatment than before treatment (P < 0.05). Discussions: After treatment, the directivity, language ability, total MMSE score and BI score of patients in the observation group were significantly higher than those in the control group (P < 0.05). Compared with the control group after treatment, the serum levels of homocysteinine (Hcy), thrombin B2 (TXB2), low-density lipoprotein cholesterol (LDL-C) and endothelin (ET) in the observation group after treatment were significantly reduced, while the levels of nitric oxide (NO), norepinephrine (NE) and dopamine (DA) were significantly increased (P < 0.05). Conclusion: The intervention of sports rehabilitation combined with huatuo reconstructive pill can promote the recovery of nerve function, improve vascular endothelial function and cognitive function in patients with vascular dementia, significantly improve the therapeutic effect, and have positive significance for the treatment of vascular dementia.