ISOLATES OF STDs CAUSATIVE AGENTS FROM SEX WORKERS ADDIS ABABA (A PRELIMINARY REPORT)

Abstract

ABSTRACT: Cervical and vaginal discharge samples, collected from282 randomly selected prostitutes of Addis Ababa, were examined for Sill causative agents. The subjects represented 900 females included in the 1990 sero-survey-for HIV infection. The results of the laboratory tests indicated that 117 (41.5%) of the examined females had a single infection by one of the five organisms tested for, while the others 18.1 % had experienced mixed infections of two organisms, and 4.2% of three organisms. The five organisms included Neisseria gonorrhoea isolated from 78 subjects (28.1 %), Trichomonas vaginalis -from 56 (20.6%), Candida albicans -from 40 (14.7%), and Gardnerella vaginosis -associated clue cells -from 27 individuals (9.9%). The presence of syphilis infection was indicated by the TPHA test in 72 subjects, representing 37.3% of the study samples. Among the N. gonorrhea isolates, PPNG strains comprised 57 (73.0%). Resistant strains were obtained to penicillin in 100.0%, ampicillin in 96.0%, bactrim (sxt) in 80.7%, among the PPNG strains; 19.1% of the NPPNG strains to penicillin, 38.1% to kanamycin, 66.6% of a bactrim and 66.7% of ampicillin. Both groups were, however, sensitive to erythromycin, tetracycline, chloramphenicol, norfloxacin, spectinomycin and ceftriaxone. Significant correlation was observed between these results and the MIC values obtained for each drug.